Briefly, the study included 120 comatose, mechanically ventilated survivors resuscitated from witnessed OHCA with ventricular tachycardia or fibrillation as the initial rhythm. The study protocol and main results have been published earlier. Six ICUs in Finland and one in Denmark participated in the COMACARE study that was conducted from March 2016 to March 2017. 3–5 poor), and we hypothesised that CVR would be impaired in patients with poor outcome. The primary outcome in this post-hoc analysis was the association between TOx and six-month neurological outcome dichotomised by cerebral performance category (CPC1-2 good vs. All patients were monitored with the same type of NIRS device over the first 48 h of ICU care enabling an estimation of CVR over time. In the multicentre randomised controlled pilot study COMACARE, 120 adult comatose mechanically ventilated survivors of OHCA with an initial rhythm of ventricular fibrillation/tachycardia were treated with low- or high-normal targets for MAP, arterial oxygen (P aO 2) and carbon dioxide (P aCO 2) tension. Impaired CVR monitored by TO x is associated with poor neurological outcomes in acute neurocritical conditions and in OHCA, as suggested by smaller, single-centre, observational cohort studies. This technique has known limitations but provides a non-invasive method to estimate CVR at the bedside. Near-infrared spectroscopy (NIRS) may be used to monitor spontaneous low-frequency oscillations in cerebral tissue oxygenation (cStO 2) that reflect CBF and, when correlated with simultaneous changes in MAP, allow for the tissue oxygenation index (TO x) to be derived as an index of dynamic CVR. The specific aspect of CVR related to MAP is commonly referred to as cerebral autoregulation. Cerebrovascular reactivity (CVR) refers to the ability of the brain vasculature to change flow resistance in response to fluctuating blood tension of oxygen and carbon dioxide and varying mean arterial blood pressure (MAP) levels, aiming to maintain a relatively constant CBF. On suggested mechanism of HIBI is ongoing cerebral hypoxia related to insufficient cerebral blood flow (CBF) after return of spontaneous circulation (ROSC). Out-of-hospital cardiac arrest (OHCA) carries a high overall mortality rate related to hypoxic-ischaemic brain injury (HIBI). Decreased upper MAP bound and a narrower MAP range for maintained CVR were associated with poor outcome and more severe brain injury assessed with NfL. Impaired CVR over 48 h was more common in patients with chronic hypertension and associated with poor outcome. NfL concentrations were higher in patients with impaired CVR compared to those with intact CVR (43 IQR vs 20 IQR pg/ml, p = 0.042). The MAP range of maintained CVR was narrower in all time intervals and intervention groups ( p < 0.05). Patients with poor outcomes had a decreased upper MAP bound of CVR over time ( p = 0.001), including the high-normal oxygen ( p = 0.002), carbon dioxide ( p = 0.012) and MAP ( p = 0.001) groups. Integrated TO x for 0–48 h was higher in patients with poor outcome than in patients with good outcome (0.89 95% CI vs. In 108 patients with sufficient data to calculate TO x, 76 patients (70%) had impaired CVR and among these, chronic hypertension was more common (58% vs. Secondary outcomes included associations with MAP bounds for CVR and biomarkers of brain injury. The primary outcome was the association between TO x and six-month functional outcome dichotomised by the cerebral performance category (CPC1-2 good vs. TO x was analysed in the 0–12, 12–24, 24–48 h time-periods and integrated over 0–48 h. The tissue oximetry index (TO x) generated by the moving correlation coefficient between cerebral tissue oxygenation measured by NIRS and MAP was used as a dynamic index of CVR with TO x > 0 indicating impaired reactivity and TO x > 0.3 used to delineate the lower and upper MAP bounds for disrupted CVR. MethodsĪ post-hoc analysis of 120 comatose OHCA patients continuously monitored with NIRS and randomised to low- or high-normal oxygen, carbon dioxide and mean arterial blood pressure (MAP) targets for 48 h. We studied the incidence and features of CVR by near infrared spectroscopy (NIRS) and associations with outcome and biomarkers of brain injury. Impaired cerebrovascular reactivity (CVR) is one feature of post cardiac arrest encephalopathy.
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These are our adjustment guidelines We can repair your shuffler whether it’s malfunctioning, moving parts are worn or damaged, the machine jams frequently, or it has any other problem. You can find all necessary information you need when you have a defective Shuffle Tech shuffler to repair “One goal of my research is to improve the scientific study of close relationships by expanding our focus to people who have been underrepresented in research, including those outside the U.S. “Close relationships are a central component of people’s lives around the world, and it is vitally important to scientifically study aspects of relationships,” Williamson said. Her research focuses on the effects of stressors such as financial strain on couple and family relationships, with metascience research directed toward improving the study of family relationships of people who have been historically underrepresented in research. Hannah Williamson, assistant professor in the Department of Human Development and Family Sciences and the Department of Psychology, will work as a visiting scholar during September 2023-May 2024 at the Universidad de Granada in Granada, Spain. “The study will form the groundwork for future discovery and preservation of these materials,” Rader said. “Beyond traditional deliverables (publications, grant proposals, bibliographic tools), this research will deepen networks for future and ongoing interinstitutional and international relationships between collectors, scholars and librarians of South Asia.” Mary Rader, South Asia librarian and head of the Fine Arts, Humanities and Global Studies Engagement Team for UT Libraries, was presented a Fulbright-Nehru Academic and Professional Excellence Award to travel in January-February 2024 to Delhi and Chennai, India, for the purpose of locating and documenting the content and condition of personal and private archives housed outside of academic and public domains. “This award will have an incredible impact on K-8 equity-focused STEM teaching and teacher education in Brazilian contexts and engaging in global conversations about race, racism and justice.” “I am so excited to begin this award and learn with and from researchers, educators and local communities in Northeast Brazil! I am grateful for … the opportunity to expand our understanding of teaching and teacher education in global contexts,” Madkins said. In July-September 2023 and November 2023-January 2024, Madkins will lecture and engage in discussions with college students and teachers while developing instructional activities and lesson plans. Tia Madkins, assistant professor of curriculum and instruction in the College of Education, received a Fulbright Flex Grant to work with the REM-NE network at Universidade Estadual de Santa Cruz in Brazil, examining how elementary and middle school mathematics teachers in Northeast Brazil develop and implement equity-focused math teaching practices. This opportunity expands the awardees’ professional networks, often leading to continued research collaborations and laying the groundwork for future partnerships between institutions. UT Austin has enjoyed a long relationship with the Fulbright Program, amassing a strong history of students, alumni, faculty members and staffers who receive Fulbright awards to work in a multitude of disciplines and attend specialized seminars across the globe. Department of State’s Bureau of Educational and Cultural Affairs. The Fulbright Program is funded through an annual appropriation made by the U.S. government’s flagship international educational exchange program, supported by the people of the United States and partner countries around the world. scholars, artists and professionals from all backgrounds teach or conduct research overseas with the program. Professors Tia Madkins and Hannah Williamson as well as head librarian Mary Rader and postdoctoral fellow Julia York will receive resources from the Fulbright Program to pursue research and/or teaching activities abroad in 2023-2024. Scholar Program awards for the 2023-2024 academic year. 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Murrow award for coverage of the Yazoo City tornado in 2010 as well as a regional Emmy for coverage of Hurricane Katrina in 2005. in 1983, he began working in television with WOLO-TV in Columbia, South Carolina, moved on to WSPA-TV in Spartanburg, South Carolina, before joining WAPT in 1986.Īs a TV meteorologist, David has won numerous awards from the Mississippi Association of Broadcasters, including Best TV Meteorologist. The university accommodates around 90 thousand students. After earning a degree in meteorology from the Pennsylvania State University Pennsylvania State University The Pennsylvania State University is an American public state-related land-grant research university. Having held this position since 1986, David Hartman is the Chief Meteorologist for WAPT. The team carries the following responsibilities.ĭavid Hartman: Chief Meteorologist at WAPT Weather WAPT Weather team offers amazing weather coverage based on the WAPT Weather radar’s prediction. She was in the Leadership Greater Jackson class of 2009-2010. The Jackson Public Schools district selected Erin as a Summer Reading Ambassador in 2014. The Links Incorporated, LeFleur’s Bluff Chapter, and Alpha Kappa Alpha Sorority, Inc. Currently, she teaches Mass Communication at Tougaloo College. In addition to working in front of the camera, Erin has also worked behind the scenes.Įrin graduated from the University of Memphis with a Bachelor of Arts in Journalism and Mississippi College with a Master of Science in Communication. A former television news reporter in Memphis, TN, Greenville, MS, and Jackson, TN, she has worked in television news for many years. Currently, she works as a member of 16 WAPT News. While working for WJTV in Jackson, Mississippi, she was the morning & noon news anchor for almost 13 years. A broadcast journalism degree was awarded to her by Ole Miss.ĭuring her almost two decades in television news, Erin Pickens has collected numerous awards. The University of Mississippi was Keegan’s first college after high school. In high school, she covered boys basketball for The George County Times and wrote for the student newspaper, The Student Press. In addition to anchoring a morning show in Tupelo, Keegan was a reporter in Hattiesburg and Columbus before arriving in Jackson in 2012. Her career as a journalist will be able to expand in the Capital City, where she is able to pursue her passion. Lucedale native Keegan Foxx graduated from George County High School and grew up in Lucedale. Keagan Foxx: Anchor at ABC Jackson Mississippi
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